The Lungs—Not the Pineal Gland—Might Be the Real DMT Factory
Hey fellow psychonauts, I was exploring the molecular similarities between melatonin, serotonin, psilocin and dmt with the help of AI and I stumbled upon something mind-blowing and wanted to share it with the community.
Many know about the DMT + pineal gland theory, the idea that our brain releases this psychedelic molecule in dreams, near-death experiences, or deep meditative states. But did you know that the lungs—not just the brain—are actually one of the body’s primary DMT factories?
The Science (Yes, this is proven!)
🔹 The enzyme Indolethylamine-N-Methyltransferase (INMT), which creates DMT, is highly active in human lung tissue.
🔹 DMT has been detected in cerebrospinal fluid, meaning it reaches the brain.
🔹 MAO enzymes immediately break it down, preventing natural "trips".
🔹 The pineal gland might still produce DMT, but it’s not the only source, maybe not even the main one.
What Does This Mean?
✅ DMT is being produced in small amounts all the time in our lungs and possibly also brain.
✅ If MAO enzymes weren’t constantly breaking it down, we might be in a permanent dream-like or psychedelic state.
✅ This raises HUGE questions about dreaming, near-death experiences, and the role of DMT in everyday consciousness.
What if we inhibited MAO naturally?
We know that ayahuasca works by blocking MAO, allowing DMT to stay in the brain long enough to induce hallucinations.
🔹 Could meditation, fasting, extreme stress, or even sleep alter this natural DMT balance?
🔹 Could near-death experiences be linked to a temporary MAO inhibition, allowing endogenous DMT to flood the brain?
🔹 What happens if someone takes an MAOI without smoking DMT, does the body’s natural DMT start building up?
I always assumed DMT was this rare, external compound, but now I realize it's actually a natural part of human biochemistry, and maybe even consciousness itself.
Would love to hear your thoughts! Does this change how you view psychedelics, dreams, or NDEs? Could our waking life already be a microdose of a constant DMT state?
edit: added source below, no this isnt just AI hallucinating garbage ...