Ketamine not working

I've decided to do oral ketamine therapy at home again. Previously I had done 200 mg every 3 days. I tried that again and no disassociation, just felt drugged for a short time, then felt wired after it.. Dr. increased to 400 mg. Still nothing. So last time I tried:

No sedatives or alcohol 12 hrs before dosing Empty stomach Dry brushing my gums Drank grapefruit juice.

Nothing.

I take Seroquel and read on here from others that Seroquel can block the effects of ketamine.

I'm taking, Luvox, Ativan, Seroquel, Gabapentin, and Amlodipine (BP med). I quit Lamactil a couple of weeks ago, I think.

Is it the Seroquel?

I would think the doctor would have caught that if this were the case. I read from others that Magnesium helps. I have bad anxiety and I wonder if my brain is fighting me and refusing to let go and let it happen. anyone else had these problems and what did you do?

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